import zipfile

def create_empty_xlsx(filename):
    with zipfile.ZipFile(filename, 'w') as zf:
        # [Content_Types].xml
        zf.writestr('[Content_Types].xml', """<?xml version="1.0" encoding="UTF-8" standalone="yes"?>
<Types xmlns="http://schemas.openxmlformats.org/package/2006/content-types">
  <Default Extension="rels" ContentType="application/vnd.openxmlformats-package.relationships+xml"/>
  <Default Extension="xml" ContentType="application/xml"/>
  <Override PartName="/xl/workbook.xml" ContentType="application/vnd.openxmlformats-officedocument.spreadsheetml.sheet.main+xml"/>
  <Override PartName="/xl/worksheets/sheet1.xml" ContentType="application/vnd.openxmlformats-officedocument.spreadsheetml.worksheet+xml"/>
</Types>""")

        # _rels/.rels
        zf.writestr('_rels/.rels', """<?xml version="1.0" encoding="UTF-8" standalone="yes"?>
<Relationships xmlns="http://schemas.openxmlformats.org/package/2006/relationships">
  <Relationship Id="rId1" Type="http://schemas.openxmlformats.org/officeDocument/2006/relationships/officeDocument" Target="xl/workbook.xml"/>
</Relationships>""")

        # xl/workbook.xml
        zf.writestr('xl/workbook.xml', """<?xml version="1.0" encoding="UTF-8" standalone="yes"?>
<workbook xmlns="http://schemas.openxmlformats.org/spreadsheetml/2006/main" xmlns:r="http://schemas.openxmlformats.org/officeDocument/2006/relationships">
  <sheets>
    <sheet name="Sheet1" sheetId="1" r:id="rId1"/>
  </sheets>
</workbook>""")

        # xl/_rels/workbook.xml.rels
        zf.writestr('xl/_rels/workbook.xml.rels', """<?xml version="1.0" encoding="UTF-8" standalone="yes"?>
<Relationships xmlns="http://schemas.openxmlformats.org/package/2006/relationships">
  <Relationship Id="rId1" Type="http://schemas.openxmlformats.org/officeDocument/2006/relationships/worksheet" Target="worksheets/sheet1.xml"/>
</Relationships>""")

        # xl/worksheets/sheet1.xml
        zf.writestr('xl/worksheets/sheet1.xml', """<?xml version="1.0" encoding="UTF-8" standalone="yes"?>
<worksheet xmlns="http://schemas.openxmlformats.org/spreadsheetml/2006/main">
  <sheetData/>
</worksheet>""")

create_empty_xlsx('test.xlsx')